Lithologies contributing to the clast population in Apollo 17 LKFM basaltic impact melts

LKFM basaltic impact melts are abundant among Apollo lunar samples, especially those from Apollo 15, 16, and 17. They are generally basaltic in composition, but are found exclusively as impact melts. They seem to be related to basins and so could represent the composition of the lower lunar crust. They contain lithic clasts that cannot be mixed in any proportion to produce the composition of the melt matrix; components rich in transition elements (Ti, Cr, Sc) and REE are not considered. To search for the mysterious cryptic component, we previously investigated the mineral clast population in two Apollo 14 LKFM basaltic impact melts, 15445 and 15455. The cryptic component was not present in the mineral clast assemblage of these breccias either, but some olivine and pyroxene grains appeared to be from lithologies not represented among identified igneous rocks from the lunar highlands. In addition, none of the mineral clasts could be unambiguously assigned to a ferroan anorthosite source. We have now extended this study to Apollo 17, starting with two LKFM impact melt breccias (76295 and 76315) from the Apollo 17 station 6 boulder. The results from the study are presented

The Complex Stratigraphy of the Highland Crust in the Serenitatis Region of the Moon Inferred from Mineral Fragment Chemistry

Large impact basins are natural drill holes into the Moon, and their ejecta carries unique information about the rock types and stratigraphy of the lunar crust. We have conducted an electron microprobe study of mineral fragments in the poikilitic melt breccias collected from the Taurus Mountains at the Apollo 17 landing site. These breccias are virtually unanimously agreed to be impact melt produced in the Serenitatis impact event. They contain lithic fragments and much more abundant mineral fragments of crustal origin. We have made precise microprobe analyses of minor element abundances in fragments of olivine, pyroxene, and plagioclase to provide new information on the possible source rocks and the crustal stratigraphy in the Serenitatis region. These data were also intended to elucidate the nature of the cryptic geochemical component in breccias such as these with low-K Fra Mauro basalt compositions. We chose the finest-grained (i.e., most rapidly quenched) breccias for study, to avoid reacted and partly assimilated fragments as much as possible. Most of the mineral fragments appear to have been derived from rocks that would fall into the pristine igneous Mg-suite as represented by lithic fragments in the Apollo collection, or reasonable extensions of it. Gabbroic rocks were more abundant in the target stratigraphy than is apparent from the Apollo sample collection. Some pyroxene and plagiociase, but probably not much olivine, could be derived from feldspathic granulites, which are metamorphosed polymict breccias. Some mineral fragments are from previously unknown rocks. These include highly magnesian olivines (up to Fo(sub 94)), possibly volcanic in origin, that exacerbate the difficulty in explaining highly magnesian rocks in the lunar crust. It appears that some part of the lunar interior has an mg*(= 100 x Mg/(Mg/Fe) atomic) greater than the conventional bulk Moon value of 80-84. Other volcanic rocks, including mare basalts, and rapidly- cooled impact melt rocks do not contribute significantly to the fragment population. Nor do ferroan anorthosites contribute more than a tiny part of even the plagiociase fragment population. A few mineral fragments that are consistent with the cryptic low-K Fra Mauro chemical component were found, and these appear to be from gabbroic sources. The mineral fragment populations cannot be mixed in their observed proportions to produce the whole rock composition, because the fragments are more refractory and deficient in Ti, P, and alkalis. A preferential contribution to the melt from a rock similar to sodic ferrogabbro can partly resolve the discrepancy. The population of mineral fragments requires a very diverse population of igenous rocks that are not all related to each other, demonstrating the existence of a complex crust built of numerous separate igneous plutons. Many of these plutons may have crystallized at shallow depths. The chemical composition of the melt breccias, in combination with the mineral fragment data and an understanding of the cratering process, suggests that the deepest crust sampled by the Serenitatis impace (not necessarily the deepest crust) was basaltic in composition, including KREEP and gabbroic rocks like sodic ferrogabbro, and lacking abundant olivine-rich material. These were overlain by Mg-suite rocks of varied types, including norites and troctolites that supplied most of the olivine mineral fragments. Granulities, which are metamorphosed and more feldspathic breccias, were abundant near the surface. Remote sensing indicates that the entire Serenitatis region lacks ferroan anorthosite, consistent with the results of our study

Role of antiplatelet therapy in cardiovascular disease II: Ischemic stroke.

The etiology of cerebrovascular disease is heterogeneous, with the majority of strokes being of ischemic origin. Transient ischemic attack is now considered to be an important precursor and long-term risk factor for ischemic stroke. Given the lack of acute therapies for ischemic stroke, current treatments focus on secondary prevention through risk-factor management, pharmacotherapy and interventional approaches. As illustrated in this paper, antiplatelet agents (e.g. clopidogrel, aspirin, dipyridamole) are the cornerstone of therapy for prevention of recurrent ischemic stroke

PTF11kx: A Type Ia Supernova with Hydrogen Emission Persisting After 3.5 Years

The optical transient PTF11kx exhibited both the characteristic spectral features of Type Ia supernovae (SNe Ia) and the signature of ejecta interacting with circumstellar material (CSM) containing hydrogen, indicating the presence of a nondegenerate companion. We present an optical spectrum at $1342$ days after peak from Keck Observatory, in which the broad component of H$\alpha$ emission persists with a similar profile as in early-time observations. We also present $Spitzer$ IRAC detections obtained $1237$ and $1818$ days after peak, and an upper limit from $HST$ ultraviolet imaging at $2133$ days. We interpret our late-time observations in context with published results - and reinterpret the early-time observations - in order to constrain the CSM's physical parameters and compare to theoretical predictions for recurrent nova systems. We find that the CSM's radial extent may be several times the distance between the star and the CSM's inner edge, and that the CSM column density may be two orders of magnitude lower than previous estimates. We show that the H$\alpha$ luminosity decline is similar to other SNe with CSM interaction, and demonstrate how our infrared photometry is evidence for newly formed, collisionally heated dust. We create a model for PTF11kx's late-time CSM interaction and find that X-ray reprocessing by photoionization and recombination cannot reproduce the observed H$\alpha$ luminosity, suggesting that the X-rays are thermalized and that H$\alpha$ radiates from collisional excitation. Finally, we discuss the implications of our results regarding the progenitor scenario and the geometric properties of the CSM for the PTF11kx system.Comment: 15 pages, 8 figures, 3 tables; submitted to Ap

Are steroid injections effective for tenosynovitis of the hand?

Yes. Steroid injections are an effective first-line therapy for flexor tenosynovitis of the hand, with a number needed to treat [NNT] of 2.3 for injection of steroids and lidocaine (strength of recommendation [SOR]: B, based on 1 prospective RCT and low- quality studies). Injection into the tendon sheath may not be critical to a successful outcome (SOR: B, based on 1 prospective uncontrolled trial)

Physical Activity in High School Classrooms: A Promising Avenue for Future Research

Adolescence represents a sensitive period whereby lifestyle factors such as physical activity can have profound, long-lasting effects on development and later life habits. However, adolescence constitutes a period of frequent sedentary behaviour. Among children, integrating physical activity into elementary school classrooms has been shown to reduce sedentary behaviour and improve academic achievement and overall physical and mental health. However, this promising area of research has not extended to adolescents and high school classrooms. In this paper, we describe the benefits of conducting research on the impact of physically active high school classrooms, and highlight the challenges and potential misconceptions associated with research in this field. Specifically, we review research on the role of physical activity in adolescent development, the benefits of classroom-based physical activity for children, and discuss the factors that may have led researchers to focus on classroom-based physical activity primarily for children, despite the potentially similar benefits for adolescents

Mineral inclusions in diamonds from Karowe Mine, Botswana: super-deep sources for super-sized diamonds?

Mineral inclusions in diamonds play a critical role in constraining the relationship between diamonds and mantle lithologies. Here we report the first major and trace element study of mineral inclusions in diamonds from the Karowe Mine in north-east Botswana, along the western edge of the Zimbabwe Craton. From a total of 107 diamonds, 134 silicate, 15 oxide, and 22 sulphide inclusions were recovered. The results reveal that 53% of Karowe inclusion-bearing diamonds derived from eclogitic sources, 44% are peridotitic, 2% have a sublithospheric origin, and 1% are websteritic. The dominant eclogitic diamond substrates sampled at Karowe are compositionally heterogeneous, as reflected in wide ranges in the CaO contents (4–16 wt%) of garnets and the Mg# (69–92) and jadeite contents (14–48 mol%) of clinopyroxenes. Calculated bulk rock REEN patterns indicate that both shallow and deep levels of the subducted slab(s) were sampled, including cumulate-like protoliths. Peridotitic garnet compositions largely derive from harzburgite/dunite substrates (~90%), with almost half the garnets having CaO contents <1.8 wt%, consistent with pyroxene-free (dunitic) sources. The highly depleted character of the peridotitic diamond substrates is further documented by the high mean and median Mg# (93.1) of olivine inclusions. One low-Ca garnet records a very high Cr2O3 content (14.7 wt%), implying that highly depleted cratonic lithosphere at the time of diamond formation extended to at least 220 km depth. Inclusion geothermobarometry indicates that the formation of peridotitic diamonds occurred along a 39–40 mW/m2 model geotherm. A sublithospheric inclusion suite is established by three eclogitic garnets containing a majorite component, a feature so far unique within the Orapa cluster. These low- and high-Ca majoritic garnets follow pyroxenitic and eclogitic trends of majoritic substitution, respectively. The origin of the majorite-bearing diamonds is estimated to be between 330 to 420 km depth, straddling the asthenosphere–transition zone boundary. This new observation of superdeep mineral inclusions in Karowe diamonds is consistent with a sublithospheric origin for the exceptionally large diamonds from this mine

SN 2015U: A Rapidly Evolving and Luminous Type Ibn Supernova

Supernova (SN) 2015U (also known as PSN J07285387+3349106) was discovered in NGC 2388 on 2015 Feb. 11. A rapidly evolving and luminous event, it showed effectively hydrogen-free spectra dominated by relatively narrow helium P-Cygni spectral features and it was classified as a SN Ibn. In this paper we present photometric, spectroscopic, and spectropolarimetric observations of SN 2015U, including a Keck/DEIMOS spectrum (resolution $\approx$ 5000) which fully resolves the optical emission and absorption features. We find that SN 2015U is best understood via models of shock breakout from extended and dense circumstellar material (CSM), likely created by a history of mass loss from the progenitor with an extreme outburst within $\sim$1-2 yr of core collapse (but we do not detect any outburst in our archival imaging of NGC 2388). We argue that the high luminosity of SN 2015U was powered not through $^{56}$Ni decay but via the deposition of kinetic energy into the ejecta/CSM shock interface. Though our analysis is hampered by strong host-galaxy dust obscuration (which likely exhibits multiple components), our dataset makes SN 2015U one of the best-studied Type Ibn supernovae and provides a bridge of understanding to other rapidly fading transients, both luminous and relatively faint.Comment: 20 pages, 15 figures, 4 table

Some extremal functions in Fourier analysis, III

We obtain the best approximation in $L^1(\R)$, by entire functions of exponential type, for a class of even functions that includes $e^{-\lambda|x|}$, where $\lambda >0$, $\log |x|$ and $|x|^{\alpha}$, where $-1 < \alpha < 1$. We also give periodic versions of these results where the approximating functions are trigonometric polynomials of bounded degree.Comment: 26 pages. Submitte